The Potential Benefits of NAD Therapy for Traumatic Brain Injury and Stroke Patients

Learn how NAD+ can benefit patients who've suffered a traumatic brain injury or stroke.


Recovering from a traumatic brain injury (TBI) or stroke is a challenging and long-term endeavor that often involves various forms of therapy and medications. Recent studies have started shedding light on the potential benefits of Nicotinamide Adenine Dinucleotide (NAD) therapy for patients who have suffered these serious neurological events. Though research is still in the early stages, the results are promising.

Disclaimer: The information presented in this blog is intended for informational purposes only and should not be construed as medical advice. Consult a healthcare professional for diagnosis and treatment options tailored to individual needs.

What is NAD?

NAD is a coenzyme found in all living cells and plays a critical role in cellular energy metabolism, DNA repair, and cellular signaling. NAD levels naturally decline as we age and can also be depleted by stress, addiction, and chronic illnesses.

The Brain and Energy

The brain is an energy-intensive organ that relies heavily on mitochondrial function for its activity. Reduced mitochondrial function has been observed in patients with TBI and stroke, leading to diminished brain activity and impaired recovery. One of the theories behind NAD therapy is that by replenishing NAD levels, one can enhance mitochondrial function and potentially improve outcomes in brain injury and stroke.

Cognitive Improvement

Some studies suggest that NAD therapy could improve cognitive function by accelerating the repair of damaged brain cells and tissues. This is particularly important in TBI and stroke recovery, where cognitive impairments are common.

Anti-Inflammatory Effects

Inflammation is often observed after a traumatic brain injury or stroke and can exacerbate the condition. NAD has anti-inflammatory properties, making it a potential candidate for reducing inflammation in the brain, which in turn could aid in quicker recovery.

Reducing Oxidative Stress

Oxidative stress is a major problem in any form of injury, including neurological ones. It can further damage brain tissue and impair recovery. NAD has antioxidant properties that help neutralize oxidative stress, thereby protecting brain cells.

Enhancing Neuroplasticity

NAD can also improve neuroplasticity, the brain’s ability to reorganize and form new neural connections. Increased neuroplasticity can aid in the rehabilitation process by allowing the brain to adapt more easily to new circumstances.

Ongoing Research

It’s important to note that while these potential benefits are promising, research is still ongoing, and more studies are needed to confirm the effectiveness of NAD therapy in TBI and stroke treatment.


NAD therapy presents an intriguing possibility for improving outcomes in TBI and stroke patients by addressing multiple mechanisms implicated in these conditions. While more research is required to establish its efficacy, the potential benefits, including enhanced mitochondrial function, cognitive improvement, anti-inflammatory effects, and reduced oxidative stress, make it an area of growing interest among healthcare professionals. Always consult with your healthcare provider before beginning any new treatment.


The NeuMed blog is published by NeuMed Modern Urgent Care + IV Therapy, an innovative urgent care and IV infusion therapy clinic with locations in Houston, Texas.

Any general advice posted on our blog, or website is for informational purposes only and is not intended to replace or substitute for any medical or other advice. If you have specific concerns or a situation arises in which you require medical advice, you should consult with an appropriately trained and qualified medical services provider.